What is Cholestin with Lipidol? Cholestin with Lipidol contains a proprietary formula including citrus fruit extract with polymethoxylated flavonoids (PMFs), palm fruit extract, geraniol, EPA and DHA to create an all natural product that targets multiple steps in the pathway of cholesterol and lipoprotein synthesis. The efficacy and safety of citrus polymethoxylated flavonoids, palm fruit extract and geraniol are supported by over 30 studies, and the cardio-friendly effects of EPA and DHA are supported by literally thousands.*

What cardiovascular health factors are targeted by Cholestin with Lipidol? Cardiovascular health factors include: 1) promotion and maintenance of desirable-levels of lipoprotein structural components (such as apo B, an LDL precursor, triglycerides, and cholesterol itself), 2) antioxidant protection, and 3) maintenance of normal inflammatory responses.*

Who should use Cholestin with Lipidol? Cholestin with Lipidol in combination with a healthy diet and moderate exercise is safe and beneficial for healthy adult men and women concerned about maintaining a normal range of existing cholesterol levels, and for whom their physician has determined that dietary supplementation is appropriate.

What is unique about Cholestin with Lipidol? Lipidol is a proprietary blend of ingredients that target multiple steps in the pathway of lipoprotein structural components (including cholesterol, apo B, and triglycerides), provides powerful antioxidants that can help protect from free radical damage, and maintenance of normal inflammatory responses.*

What ingredients does Cholestin with Lipidol provide? Each soft gel cap of Cholestin provides 525 milligrams of Lipidol: a proprietary blend including citrus fruit extract with polymethoxylated flavonoids, tocotrienols from palm fruit, geraniol, EPA and DHA from cold water fish.

What is the source of each ingredient in Cholestin with Lipidol? Citrus polymethoxylated flavonoids are extracted from the peel of oranges. Tocotrienols are delivered from red palm fruit extract; EPA and DHA are sourced from the purest cold water fish available, and geraniol (a compound found naturally in many plants and fruits) is delivered in a nature-identical form.

Is Cholestin with Lipidol safe? All the ingredients in Cholestin with Lipidol have been shown to be safe at the amounts recommended.

Are there any side effects of Cholestin with Lipidol? No side effects have been reported in the studies conducted on the ingredients in Cholestin with Lipidol.

Are there any contraindications or known drug interactions with Cholestin with Lipidol?
Preliminary data suggest polymethoxylated flavonoids found in Cholestin with Lipidol may inhibit the efficacy of oral tamoxifen, and should therefore not be taken concurrently with antiproliferative drugs.

Individuals taking statin drugs must consult with their physician prior to taking Cholestin with Lipidol.
We cannot make medical recommendations, or recommend that Cholestin with Lipidol be taken with statin drugs, only you and your doctor can decide.

Are there any grapefruit derived ingredients in Cholestin with Lipidol? Cholestin with Lipidol contains citrus extract from orange peels; grapefruit is not a component of Lipidol.
The grapefruit flavonoids implicated with the suppression of P450 enzymes are not present at significant levels in Cholestin with Lipidol.

Is there anyone who should not use this product? Cholesterol is an important building block to developing a fetus; women in their childbearing years should consult with a physician prior to taking Cholestin with Lipidol.

What are the health benefits of each of the ingredients in Cholestin with Lipidol?
Lipidol targets multiple aspects of cardiovascular health including:
1) promotion and maintenance of desirable-levels of lipoprotein structural components
2) antioxidant protection
3) maintenance of normal inflammatory responses

References

Choi HS, Song HS, Ukeda H, Sawamura M. Radical-scavenging activities of citrus essential oils and their components: detection using 1,1-diphenyl-2-picrylhydrazyl. J Agric Food Chem. 2000 Sep;48(9):4156-61

Endres S, Meydani SN, Dinarello CA. Effects of omega-3 fatty acid supplements on ex vivo synthesis of cytokines in human volunteers. World Rev Nutr Diet 1991;66:401-406.

Davidson MR, Maki KC, Kalkowski J, et al. Effects of docosahexaenoic acid on serum lipoproteins in patients with combined hyperlipidemia: A randomized, double-blind, placebo-controlled trial. J Am Coll Nutr 1997;16:236-243.

Manthey JA. Biological properties of flavonoids pertaining to inflammation. Microcirculation. 2000;7:S29-S34.

Peffley DM, Gayen AK. Plant-derived monoterpenes suppress hamster kidney cell 3-hydroxy-3-methylglutaryl coenzyme a reductase synthesis at the post-transcriptional level. J Nutr 2003;133:38-44.

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